Testing and management for monoclonal gammopathy of uncertain significance and myeloma patients presenting with osteoporosis and fragility fractures.

Nador, Guido and Ramasamy, Karthik and Panitsas, Fotios and Pratt, Guy and Sadler, Ross and Javaid, Muhammad Kassim (2019) Testing and management for monoclonal gammopathy of uncertain significance and myeloma patients presenting with osteoporosis and fragility fractures. Rheumatology (Oxford, England), 58 (7). pp. 1142-1153. ISSN 1462-0332. This article is available to all UHB staff and students [one year embargo] via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Abstract

Multiple myeloma, the second most frequent blood cancer, and its precursor, monoclonal gammopathy of uncertain significance, are associated with an increased risk of fragility fractures. However, current guidelines fail to offer explicit indications for healthcare professionals in terms of testing and thresholds for onward referral. The purpose of this review is to present the association of these conditions and metabolic bone disease and to highlight the importance of considering a diagnosis of monoclonal gammopathy of uncertain significance and myeloma in the context of a secondary fracture prevention assessment and of a multidisciplinary approach in managing these patients.

Item Type: Article
Additional Information: This article is available to all UHB staff and students [one year embargo] via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: QZ Pathology. Oncology
WE Musculoskeletal. Orthopaedics
Divisions: Planned IP Care > Oncology and Clinical Haematology
Related URLs:
Depositing User: Miss Emily Johnson
Date Deposited: 28 Jun 2019 13:21
Last Modified: 28 Jun 2019 13:21
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/2190

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