Instrument-based Tests for Measuring Anterior Chamber Cells in Uveitis: A Systematic Review.

Liu, Xiaoxuan and Solebo, Ameenat L and Faes, Livia and Beese, Sophie and Braithwaite, Tasanee and Round, Matthew E and Panthagani, Jesse and Kale, Aditya U and McNally, Thomas W and Abdulla, Didar and Keane, Pearse A and Moore, David J and Denniston, Alastair K (2019) Instrument-based Tests for Measuring Anterior Chamber Cells in Uveitis: A Systematic Review. Ocular immunology and inflammation. pp. 1-12. ISSN 1744-5078. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: https://www.tandfonline.com/doi/full/10.1080/09273...

Abstract

: New instrument-based techniques for anterior chamber (AC) cell counting can offer automation and objectivity above clinician assessment. This review aims to identify such instruments and its correlation with clinician estimates. : Using standard systematic review methodology, we identified and tabulated the outcomes of studies reporting reliability and correlation between instrument-based measurements and clinician AC cell grading. : From 3470 studies, 6 reported correlation between an instrument-based AC cell count to clinician grading. The two instruments were optical coherence tomography (OCT) and laser flare-cell photometry (LFCP). Correlation between clinician grading and LFCP was 0.66-0.87 and 0.06-0.97 between clinician grading and OCT. OCT volume scans demonstrated correlation between 0.75 and 0.78. Line scans in the middle AC demonstrated higher correlation (0.73-0.97) than in the inferior AC (0.06-0.56). : AC cell count by OCT and LFP can achieve high levels of correlation with clinician grading, whilst offering additional advantages of speed, automation, and objectivity.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WW Eyes. Ophthalmology
Divisions: Ambulatory Care > Ophthalmology
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Depositing User: Mr Philip O'Reilly
Date Deposited: 23 Aug 2019 13:23
Last Modified: 23 Aug 2019 13:23
URI: http://www.repository.uhblibrary.co.uk/id/eprint/2325

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