Clinical classification of adult patients with chronic intestinal failure due to benign disease: An international multicenter cross-sectional survey.

Pironi, Loris and Konrad, Denise and Brandt, Chrisoffer and Joly, Francisca and Wanten, Geert and Agostini, Federica and Chambrier, Cecile and Aimasso, Umberto and Zeraschi, Sarah and Kelly, Darlene and Szczepanek, Kinga and Jukes, Amelia and Di Caro, Simona and Theilla, Miriam and Kunecki, Marek and Daniels, Joanne and Serlie, Mireille and Poullenot, Florian and Wu, Jian and Cooper, Sheldon C and Rasmussen, Henrik H and Compher, Charlene and Seguy, David and Crivelli, Adriana and Pagano, Maria C and Hughes, Sarah-Jane and Guglielmi, Francesco W and Kozjek, Nada Rotovnik and Schneider, Stéphane M and Gillanders, Lyn and Ellegard, Lars and Thibault, Ronan and Matras, Przemysław and Zmarzly, Anna and Matysiak, Konrad and Van Gossum, Andrè and Forbes, Alastair and Wyer, Nicola and Taus, Marina and Virgili, Nuria M and O'Callaghan, Margie and Chapman, Brooke and Osland, Emma and Cuerda, Cristina and Sahin, Peter and Jones, Lynn and Lee, Andre D W and Bertasi, Valentino and Orlandoni, Paolo and Izbéki, Ferenc and Spaggiari, Corrado and Díez, Marta Bueno and Doitchinova-Simeonova, Maryana and Garde, Carmen and Serralde-Zúñiga, Aurora E and Olveira, Gabriel and Krznaric, Zeljko and Czako, Laszlo and Kekstas, Gintautas and Sanz-Paris, Alejandro and Jáuregui, Estrella Petrina and Murillo, Ana Zugasti and Schafer, Eszter and Arends, Jann and Suárez-Llanos, José P and Shaffer, Jon and Lal, Simon (2018) Clinical classification of adult patients with chronic intestinal failure due to benign disease: An international multicenter cross-sectional survey. Clinical nutrition (Edinburgh, Scotland), 37 (2). pp. 728-738. ISSN 1532-1983. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.comz795c8c bu using their UHB Athens login IDs

Full text not available from this repository.
Official URL: ttps://www.clinicalnutritionjournal.com/article/S0...

Abstract

BACKGROUND & AIMS

The aim of the study was to evaluate the applicability of the ESPEN 16-category clinical classification of chronic intestinal failure, based on patients' intravenous supplementation (IVS) requirements for energy and fluids, and to evaluate factors associated with those requirements.

METHODS

ESPEN members were invited to participate through ESPEN Council representatives. Participating centers enrolled adult patients requiring home parenteral nutrition for chronic intestinal failure on March 1st 2015. The following patient data were recorded though a structured database: sex, age, body weight and height, intestinal failure mechanism, underlying disease, IVS volume and energy need.

RESULTS

Sixty-five centers from 22 countries enrolled 2919 patients with benign disease. One half of the patients were distributed in 3 categories of the ESPEN clinical classification. 9% of patients required only fluid and electrolyte supplementation. IVS requirement varied considerably according to the pathophysiological mechanism of intestinal failure. Notably, IVS volume requirement represented loss of intestinal function better than IVS energy requirement. A simplified 8 category classification of chronic intestinal failure was devised, based on two types of IVS (either fluid and electrolyte alone or parenteral nutrition admixture containing energy) and four categories of volume.

CONCLUSIONS

Patients' IVS requirements varied widely, supporting the need for a tool to homogenize patient categorization. This study has devised a novel, simplified eight category IVS classification for chronic intestinal failure that will prove useful in both the clinical and research setting when applied together with the underlying pathophysiological mechanism of the patient's intestinal failure.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.comz795c8c bu using their UHB Athens login IDs
Subjects: WI Digestive system. Gastroenterology
Divisions: Planned IP Care > Gastroentrology
Related URLs:
Depositing User: Jamie Edgar
Date Deposited: 30 Sep 2019 08:36
Last Modified: 02 Oct 2019 15:11
URI: http://www.repository.uhblibrary.co.uk/id/eprint/2426

Actions (login required)

View Item View Item