Machine perfusion in liver transplantation: an essential treatment or just an expensive toy?

Schlegel, Andrea A and Kalisvaart, Marit and Muiesan, Paolo (2018) Machine perfusion in liver transplantation: an essential treatment or just an expensive toy? Minerva anestesiologica, 84 (2). pp. 236-245. ISSN 1827-1596.

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Official URL: https://www.minervamedica.it/en/journals/minerva-a...

Abstract

This review focuses on recent developments in preservation techniques in liver transplantation. First, we discuss mechanisms of organ injury when using high-risk organs, including donation after circulatory death and steatotic grafts and we summarize pathways of ischemia reperfusion injury together with their link to the immune response. Second, we report on improvement strategies of marginal liver grafts by different machine perfusion concepts and summarize perfusion approaches with recent clinical implementation.

Item Type: Article
Subjects: WO Surgery
Divisions: Planned IP Care
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Depositing User: Jennifer Manders
Date Deposited: 08 Nov 2019 16:01
Last Modified: 08 Nov 2019 16:01
URI: http://www.repository.uhblibrary.co.uk/id/eprint/2584

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