An in vitro comparison of standard cleaning to a continuous passive disinfection cap for the decontamination of needle-free connectors.

Casey, Anna L and Karpanen, Tarja J and Nightingale, Peter and Elliott, Tom S J (2018) An in vitro comparison of standard cleaning to a continuous passive disinfection cap for the decontamination of needle-free connectors. Antimicrobial resistance and infection control, 7. p. 50. ISSN 2047-2994. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Abstract

Background

The optimal decontamination method for needle-free connectors is still unresolved. The objective of this study was to determine if a continuous passive disinfection cap is as effective as standard cleaning for the microbial decontamination of injection ports of two types of needle-free connectors.

Methods

The injection ports of needle-free connectors were inoculated with and allowed to dry. Disinfection caps containing 70% (/) isopropyl alcohol (IPA) were attached to the connectors for one, three or 7 days and were compared with needle-free connectors cleaned with 2% (/) chlorhexidine gluconate (CHG) in 70% () IPA. The number of remaining on the injection ports was evaluated. Median log reductions and 95% confidence interval (CI) were calculated and data analyzed using the Mann-Whitney test.

Results

The application of the disinfection cap resulted in a significantly higher reduction in than the 2% (/) CHG in 70% (/) IPA wipe, achieving a > 5 Log reduction in CFU at each time point.

Conclusions

The disinfection caps resulted in a significantly higher reduction in on the injection ports when compared to the use of a 2% () CHG in 70% () IPA wipe. This offers an explanation for the lower rates of central-line associated bloodstream infection (CLABSI) associated with the use of disinfection caps reported in clinical studies.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: QW Microbiology. Immunology
Divisions: Clinical Support > Infection Control
Related URLs:
Depositing User: Mrs Semanti Chakraborty
Date Deposited: 31 Dec 2019 12:39
Last Modified: 31 Dec 2019 12:39
URI: http://www.repository.uhblibrary.co.uk/id/eprint/2720

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