Post-transplant Monoclonal Gammopathy of Renal Significance: A Case Series.

Rana, Ritika and Cockwell, Paul and Pratt, Guy and Cook, Mark and Drayson, Mark and Vydianath, Bindu and Neil, Desley and Pinney, Jennifer H (2020) Post-transplant Monoclonal Gammopathy of Renal Significance: A Case Series. Transplantation proceedings. ISSN 1873-2623. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Abstract

Monoclonal gammopathy of renal significance (MGRS) is a new concept with evolving evidence for treatment. MGRS in the transplant kidney is a rare cause of renal transplant dysfunction that can lead to graft loss. Most cases of post-transplant MGRS are due to recurrent disease. Clone-specific chemotherapy is required to target the underlying clone, and this may improve graft survival; however, this can be challenging, as most patients are elderly with age-related comorbidities and may have complications associated with increasing immunosuppression. Here, we report 3 cases of renal allograft MGRS, and each case highlights different challenges in the diagnosis and management of this condition.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: QW Microbiology. Immunology
WJ Urogenital system. Urology
Divisions: Emergency Services > Renal
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Depositing User: Mr Philip O'Reilly
Date Deposited: 13 Mar 2020 15:19
Last Modified: 13 Mar 2020 15:19
URI: http://www.repository.uhblibrary.co.uk/id/eprint/2930

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