Non-invasive Instrument-Based Tests for Quantifying Anterior Chamber Flare in Uveitis: A Systematic Review.

Liu, Xiaoxuan and McNally, Thomas W and Beese, Sophie and Downie, Laura E and Solebo, Ameenat L and Faes, Livia and Husain, Syed and Keane, Pearse A and Moore, David J and Denniston, Alastair K (2020) Non-invasive Instrument-Based Tests for Quantifying Anterior Chamber Flare in Uveitis: A Systematic Review. Ocular immunology and inflammation. pp. 1-9. ISSN 1744-5078.

Full text not available from this repository.
Official URL: https://www.tandfonline.com/doi/abs/10.1080/092739...

Abstract

: Anterior chamber (AC) flare is a key sign for anterior uveitis. New instrument-based techniques for measuring AC flare can offer automation and objectivity. This review aims to identify objective instrument-based measures for AC flare.: In this systematic review, we identified studies reporting correlation between instrument-based tests versus clinician AC flare grading, and/or aqueous protein concentration, as well as test reliability.: Four index tests were identified in 11 studies: laser-flare photometry (LFP), optical coherence tomography, ocular flare analysis meter (OFAM) and the double-pass technique. The correlation between LFP and clinician grading was 0.40-0.93 and 0.87-0.94 for LFP and protein concentration. The double-pass technique showed no correlation with clinician grading and insufficient information was available for OFAM.: LFP shows moderate to strong correlation with clinician grading and aqueous protein concentration. LFP could be a superior reference test compared to clinician AC flare grading for validating new index tests.

Item Type: Article
Subjects: WW Eyes. Ophthalmology
Divisions: Ambulatory Care > Ophthalmology
Related URLs:
Depositing User: Mrs Yolande Brookes
Date Deposited: 10 Apr 2020 15:50
Last Modified: 10 Apr 2020 15:50
URI: http://www.repository.uhblibrary.co.uk/id/eprint/2986

Actions (login required)

View Item View Item