Use of genome sequencing to identify hepatitis C virus transmission in a renal healthcare setting.

Garvey, M I, Bradley, C W, Holden, K L, Hewins, P, Ngui, S-L, Tedder, R, Jumaa, P and Smit, E (2017) Use of genome sequencing to identify hepatitis C virus transmission in a renal healthcare setting. The Journal of hospital infection. ISSN 1532-2939. This article is available to all HEFT staff and students via ASK HEFT Discovery tool www.heftlibrary.nhs.uk using their HEFT Athens Login.

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Abstract

BACKGROUND

Hepatitis C virus (HCV) infection is a major health burden worldwide. A patient with no history of HCV infection while on a renal unit was found to seroconvert to HCV.

AIM

To report the use of sequencing to postulate how transmission of HCV occurred in a healthcare setting, and how this guided our outbreak investigation.

FINDINGS

Based on infection control inspections the transmission event was surmised to be due to ward environmental contamination with blood and subsequent inoculation from intravenous interventions on the patient acquiring HCV. We discuss the interventions put in place in response to the outbreak investigation findings.

CONCLUSION

Sequencing of healthcare-acquired HCV infections should be undertaken as routine practice in outbreak investigations.

Item Type:	Article
Additional Information:	This article is available to all HEFT staff and students via ASK HEFT Discovery tool www.heftlibrary.nhs.uk using their HEFT Athens Login.
Subjects:	WC Communicabable diseases WI Digestive system. Gastroenterology
Divisions:	Clinical Support > Pathology
Related URLs:	https://www.ncbi.nlm.nih.gov/pubmed/2819...
Depositing User:	Mrs Yolande Brookes
Date Deposited:	16 Mar 2017 11:38
Last Modified:	16 Mar 2017 11:38
URI:	http://www.repository.uhblibrary.co.uk/id/eprint/1270

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