Tools
Tools
Hassan, Fadi, Murrell, William D, Refalo, Andrew and Maffulli, Nicola (2018) Alternatives to Biologics in Management of Knee Osteoarthritis: A Systematic Review. Sports medicine and arthroscopy review, 26 (2). pp. 79-85. ISSN 1538-1951. This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs
Full text not available from this repository.Abstract
BACKGROUND
Knee osteoarthritis (KOA) is a common condition encountered by physicians. KOA is addressed by a wide array of modalities including a number of nonbiological treatments.
METHODS
PubMed, ISI Web of Science, and SPORTDiscus were searched for level 1 to 4 studies published from inception to August 2017.
RESULTS
A total of 18 studies were evaluated and results demonstrated moderate supporting evidence for prolotherapy and limited evidence for botulinum toxin type A, sodium bicarbonate and calcium gluconate, and low-molecular weight fraction of 5% human serum albumin. Evidence for local anesthetic agents was conflicting.
CONCLUSION
There is moderate supportive evidence for the effectiveness of prolotherapy in improving pain and function in both, short-term and long-term. Limited supporting evidence found for botulinum toxin type A, sodium bicarbonate and calcium gluconate, and low-molecular weight fraction of 5% human serum albumin in improving pain and function. There is conflicting evidence for the use of local anesthetic agents in patients with KOA.
| Item Type: | Article |
|---|---|
| Additional Information: | This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs |
| Subjects: | WD Diseases and disorders of systemic, metabolic or environmental origin > WD811 Rheumatology WE Musculoskeletal. Orthopaedics |
| Divisions: | Planned IP Care > Trauma and Orthopaedics |
| Related URLs: | |
| Depositing User: | Mrs Caroline Tranter |
| Date Deposited: | 04 May 2018 13:29 |
| Last Modified: | 04 May 2018 13:29 |
| URI: | http://www.repository.uhblibrary.co.uk/id/eprint/1640 |
Actions (login required)
 |
View Item |
