Robotic lateral oropharyngectomy following diagnostic tonsillectomy is oncologically safe in patients with high risk human papillomavirus related squamous cell cancer.

Siddiq, Somiah, Cartlidge, David, Stephen, Sarah, Sathasivam, Hans P, Fox, Hannah, O'Hara, James, Meikle, David, Iqbal, Muhammad Shahid, Kelly, Charles G, Robinson, Max and Paleri, Vinidh (2018) Robotic lateral oropharyngectomy following diagnostic tonsillectomy is oncologically safe in patients with high risk human papillomavirus related squamous cell cancer. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. ISSN 1434-4726. This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs

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Abstract

PURPOSE

Diagnostic tonsillectomy is rarely an oncologic operation owing to close or positive margins. The standard of care is for further treatment to the primary site, typically with adjuvant radiotherapy.

METHODS

14 patients with close or positive margins following a diagnostic tonsillectomy underwent transoral robotic surgery (TORS) and lateral oropharyngectomy; five patients with the longest follow-up had their excision specimens examined with a step serial sectioning technique (SSS).

RESULTS

Conventional histopathological examination of the TORS resection specimens did not demonstrate residual carcinoma in 13 patients, confirmed by examination using SSS in 5 patients. There were no post-operative complications or long-term functional deficit. Seven patients received surgery alone with 100% overall and disease specific survival, respectively (median follow-up 27.5 months; range 5.2-50.4).

CONCLUSIONS

This prospective study suggests that TORS lateral oropharyngectomy alone is an oncologically safe treatment when close or positive margins are identified on diagnostic tonsillectomy in HPV-positive SCC.

Item Type:	Article
Additional Information:	This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs
Subjects:	WV Otorhinolaryngology. ENT medicine
Divisions:	Ambulatory Care > ENT
Related URLs:	https://www.ncbi.nlm.nih.gov/pubmed/2975...
Depositing User:	Mr Philip O'Reilly
Date Deposited:	04 Jun 2018 13:13
Last Modified:	04 Jun 2018 13:13
URI:	http://www.repository.uhblibrary.co.uk/id/eprint/1659

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