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Rajabally, Yusuf A and Attarian, Shahram (2018) Chronic inflammatory demyelinating polyneuropathy and malignancy: A systematic review. Muscle & nerve, 57 (6). pp. 875-883. ISSN 1097-4598. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Full text not available from this repository.Abstract
A systematic review of the literature was performed on the association of chronic inflammatory demyelinating polyneuropathy (CIDP) with malignancy. Hematological disorders are the most common association, particulalry non-Hodgkin lymphoma. CIDP frequently precedes the malignancy diagnosis, and there is a favorable CIDP response to treatment more than 70% of the time. Melanoma is the second most common association and may be accompanied by antiganglioside antibodies; CIDP shows a good response to immunotherapy. Other cancers are rare, with variable timings and presentations but good responses to immunomodulation and/or cancer therapy. Unusual neurological features such as ataxia, distal/upper limb predominance, or cranial/respiratory/autonomic involvement may suggest associated malignancy as may abdominal pain, diarrhea/constipation, poor appetite/weight loss, dermatological lesions, and lymphadenopathy. In the appropriate clinical and electrophysiological setting, CIDP associated with cancer should be considered. Immunomodulatory therapy, cancer treatment alone, or a combination may be effective. Muscle Nerve 57: 875-883, 2018.
| Item Type: | Article |
|---|---|
| Additional Information: | This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs |
| Subjects: | WL Nervous system. Neurology |
| Divisions: | Emergency Services > Neurology |
| Related URLs: | |
| Depositing User: | Mrs Semanti Chakraborty |
| Date Deposited: | 21 Jun 2019 14:23 |
| Last Modified: | 21 Jun 2019 14:23 |
| URI: | http://www.repository.uhblibrary.co.uk/id/eprint/2171 |
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