Large-duct cholangiopathies: aetiology, diagnosis and treatment.

Menon, Shyam and Holt, Andrew (2019) Large-duct cholangiopathies: aetiology, diagnosis and treatment. Frontline gastroenterology, 10 (3). pp. 284-291. ISSN 2041-4137. This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs

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Abstract

Cholangiopathies describe a group of conditions affecting the intrahepatic and extrahepatic biliary tree. Impairment to bile flow and chronic cholestasis cause biliary inflammation, which leads to more permanent damage such as destruction of the small bile ducts (ductopaenia) and biliary cirrhosis. Most cholangiopathies are progressive and cause end-stage liver disease unless the physical obstruction to biliary flow can be reversed. This review considers large-duct cholangiopathies, such as primary sclerosing cholangitis, ischaemic cholangiopathy, portal biliopathy, recurrent pyogenic cholangitis and Caroli disease.

Item Type:	Article
Additional Information:	This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs
Subjects:	WI Digestive system. Gastroenterology
Divisions:	Planned IP Care > Gastroentrology
Related URLs:	https://www.ncbi.nlm.nih.gov/pubmed/3128...
Depositing User:	Mrs Yolande Brookes
Date Deposited:	12 Jul 2019 12:48
Last Modified:	12 Jul 2019 12:48
URI:	http://www.repository.uhblibrary.co.uk/id/eprint/2224

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