Elevation of serum creatinine in a renal transplant patient following oral creatine supplementation.

Law, Jonathan Philip, Di Gerlando, Saveria, Pankhurst, Tanya and Kamesh, Lavanya (2019) Elevation of serum creatinine in a renal transplant patient following oral creatine supplementation. Clinical kidney journal, 12 (4). pp. 600-601. ISSN 2048-8505. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

Preview

Text (PDF file format) ckj.pdf - Published Version Available under License Creative Commons Attribution 4.0. Download (271kB) | Preview

Abstract

We report the case of a renal transplant recipient presenting with elevated serum creatinine levels whilst taking oral creatine ethyl ester (CEE), but not creatine monohydrate (CM). Standard investigations for allograft dysfunction, including Doppler ultrasound and renal biopsy, were normal. Serum creatinine normalized following cessation of the supplement. CM is poorly absorbed and does not affect creatinine. In contrast, CEE is converted and absorbed as creatinine, elevating serum levels. In such cases, creatinine is not a valid surrogate for glomerular filtration rate (GFR). Alternate methods of GFR measurement should be considered and a rigorous clinical and drug history taken.

Item Type:	Article
Additional Information:	This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects:	WJ Urogenital system. Urology
Divisions:	Emergency Services > Renal
Related URLs:	https://www.ncbi.nlm.nih.gov/pubmed/3138...
Depositing User:	Mrs Yolande Brookes
Date Deposited:	09 Aug 2019 15:23
Last Modified:	09 Aug 2019 15:23
URI:	http://www.repository.uhblibrary.co.uk/id/eprint/2301

Actions (login required)

View Item