Instrument-based Tests for Measuring Anterior Chamber Cells in Uveitis: A Systematic Review.

Liu, Xiaoxuan, Solebo, Ameenat L, Faes, Livia, Beese, Sophie, Braithwaite, Tasanee, Round, Matthew E, Panthagani, Jesse, Kale, Aditya U, McNally, Thomas W, Abdulla, Didar, Keane, Pearse A, Moore, David J and Denniston, Alastair K (2019) Instrument-based Tests for Measuring Anterior Chamber Cells in Uveitis: A Systematic Review. Ocular immunology and inflammation. pp. 1-12. ISSN 1744-5078. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: https://www.tandfonline.com/doi/full/10.1080/09273...

Abstract

: New instrument-based techniques for anterior chamber (AC) cell counting can offer automation and objectivity above clinician assessment. This review aims to identify such instruments and its correlation with clinician estimates. : Using standard systematic review methodology, we identified and tabulated the outcomes of studies reporting reliability and correlation between instrument-based measurements and clinician AC cell grading. : From 3470 studies, 6 reported correlation between an instrument-based AC cell count to clinician grading. The two instruments were optical coherence tomography (OCT) and laser flare-cell photometry (LFCP). Correlation between clinician grading and LFCP was 0.66-0.87 and 0.06-0.97 between clinician grading and OCT. OCT volume scans demonstrated correlation between 0.75 and 0.78. Line scans in the middle AC demonstrated higher correlation (0.73-0.97) than in the inferior AC (0.06-0.56). : AC cell count by OCT and LFP can achieve high levels of correlation with clinician grading, whilst offering additional advantages of speed, automation, and objectivity.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WW Eyes. Ophthalmology
Divisions: Ambulatory Care > Ophthalmology
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Depositing User: Mr Philip O'Reilly
Date Deposited: 23 Aug 2019 13:23
Last Modified: 23 Aug 2019 13:23
URI: http://www.repository.uhblibrary.co.uk/id/eprint/2325

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