Storiform collagenoma (sclerotic fibroma) of the oral mucosa.

Elledge, R, Nandra, B, Bates, T, Zardo, Davide and Parmar, S (2019) Storiform collagenoma (sclerotic fibroma) of the oral mucosa. The British journal of oral & maxillofacial surgery. ISSN 1532-1940.

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Storiform collagenoma (also called sclerotic fibroma) is uncommon, occurs as a cutaneous fibrous neoplasm, and is particularly rare in mucosal tissue in the head and neck. We describe an unexpected diagnosis in the oral cavity. Histopathological examination showed a proliferation of fibrous tissue, which was well circumscribed but unencapsulated, with thick laminated bundles of eosinophilic collagen that exhibited a storiform or "whorled" pattern. First described by Weary et al in 1972, storiform collagenoma is a marker for Cowden's disease or PTEN hamartoma tumour syndrome. Identification of other synchronous lesions should prompt chromosomal analysis for a mutation in the PTEN gene on chromosome 10q23.

Item Type: Article
Subjects: WO Surgery
Divisions: Planned IP Care > General Surgery
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Depositing User: Mr Muneeb Liaquat
Date Deposited: 29 Nov 2019 14:58
Last Modified: 29 Nov 2019 14:58

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