Model-based economic evaluations of diagnostic point of care tests were rarely fit for purpose.

Breheny, Katie, Sutton, Andrew J and Deeks, Jonathan J (2019) Model-based economic evaluations of diagnostic point of care tests were rarely fit for purpose. Journal of clinical epidemiology, 109. pp. 1-11. ISSN 1878-5921. This article is available to all UHB staff and students via ASK Discovery tool using their UHB Open Athens account

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Official URL: https://www.jclinepi.com/article/S0895-4356(18)307...

Abstract

OBJECTIVES

Linked evidence models are recommended to predict health benefits and cost-effectiveness of diagnostic tests. We considered how published models accounted for changes in patient pathways that occur with point of care tests (POCTs) and their impact on patient health and costs.

STUDY DESIGN AND SETTING

Model-based evaluations of diagnostic POCTs published from 2004 to 2017 were identified from searching six databases. For each model, we assessed the outcomes considered, and whether reduced time to diagnosis and increased access to testing affected patient health and costs.

RESULTS

Seventy-four model-based evaluations were included: 95% incorporated evidence on test accuracy, but 34% only assessed intermediate outcomes such as rates of correct diagnosis. Of 54 models where POCTs reduced testing time, 39% addressed the economic and 37% addressed the health benefits of faster diagnosis. No model considered differences in access to tests.

CONCLUSION

Many models fail to capture the effects of POCTs in increasing access, advancing speed of diagnosis and treatment, and reducing anxiety and the associated costs. Many only consider the impact of testing from changes in accuracy. Ensuring models incorporate changes in patient pathways from faster and more accessible testing will lead to economic evaluations that better reflect the impact of POCTs.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool using their UHB Open Athens account
Subjects: WB Practice of medicine
Divisions: Ambulatory Care
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Depositing User: Beth Connors
Date Deposited: 11 May 2020 14:29
Last Modified: 11 May 2020 14:29
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3060

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