SARS-CoV-2 serology: Test, test, test, but interpret with caution!

Bermingham, William H, Wilding, Thomas, Beck, Sarah C and Huissoon, Aarnoud P (2020) SARS-CoV-2 serology: Test, test, test, but interpret with caution! Clinical medicine (London, England). ISSN 1473-4893. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: https://www.rcpjournals.org/content/clinmedicine/e...

Abstract

SARS-CoV-2 serological tests are a subject of intense interest and have the potential to significantly enhance the diagnostic capability of healthcare services in the current pandemic. However, as with all novel assays, significant validation is required to understand the clinical relevance of results.We present the first study to assess clinician interpretation of SARS-CoV-2 serology scenarios. We identify common key assumptions regarding patient infectivity and protection that are not currently supported by the SARS-CoV-2 evidence base. In this rapidly developing field, we therefore strongly recommend serological assay results are accompanied by clear interpretive support from laboratory and infectious diseases specialists.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: W Public health. Health statistics. Occupational health. Health education
WC Communicabable diseases
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Depositing User: Mrs Yolande Brookes
Date Deposited: 10 Jun 2020 14:10
Last Modified: 10 Jun 2020 14:10
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3159

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