Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology.

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Neuberger, James, Patel, Jai, Caldwell, Helen, Davies, Susan, Hebditch, Vanessa, Hollywood, Coral, Hubscher, Stefan, Karkhanis, Salil, Lester, Will, Roslund, Nicholas, West, Rebecca, Wyatt, Judith I and Heydtmann, Mathis (2020) Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology. Gut. ISSN 1468-3288. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: https://gut.bmj.com/

Abstract

Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes. There are several approaches to liver biopsy but predominantly percutaneous or transvenous approaches are used. A wide choice of needles is available and the approach and type of needle used will depend on the clinical state of the patient and local expertise but, for non-lesional biopsies, a 16-gauge needle is recommended. Many patients with liver disease will have abnormal laboratory coagulation tests or receive anticoagulation or antiplatelet medication. A greater understanding of the changes in haemostasis in liver disease allows for a more rational, evidence-based approach to peri-biopsy management. Overall, liver biopsy is safe but there is a small morbidity and a very small mortality so patients must be fully counselled. The specimen must be of sufficient size for histopathological interpretation. Communication with the histopathologist, with access to relevant clinical information and the results of other investigations, is essential for the generation of a clinically useful report.

Item Type:	Article
Additional Information:	This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects:	QZ Pathology. Oncology WH Haemic and lymphatic systems. Haematology WI Digestive system. Gastroenterology WN Medical imaging. Radiology
Divisions:	Planned IP Care > Gastroentrology
Related URLs:	https://pubmed.ncbi.nlm.nih.gov/
Depositing User:	Jamie Edgar
Date Deposited:	11 Jun 2020 10:48
Last Modified:	11 Jun 2020 10:48
URI:	http://www.repository.uhblibrary.co.uk/id/eprint/3165

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