The impact of ethnicity on clinical outcomes in COVID-19: A systematic review.

Pan, Daniel, Sze, Shirley, Minhas, Jatinder S, Bangash, Mansoor N, Pareek, Nilesh, Divall, Pip, Williams, Caroline Ml, Oggioni, Marco R, Squire, Iain B, Nellums, Laura B, Hanif, Wasim, Khunti, Kamlesh and Pareek, Manish (2020) The impact of ethnicity on clinical outcomes in COVID-19: A systematic review. EClinicalMedicine, 23. p. 100404. ISSN 2589-5370. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

Full text not available from this repository.
Official URL: https://www.thelancet.com/journals/eclinm/home

Abstract

Background

The relationship between ethnicity and COVID-19 is uncertain. We performed a systematic review to assess whether ethnicity has been reported in patients with COVID-19 and its relation to clinical outcomes.

Methods

We searched EMBASE, MEDLINE, Cochrane Library and PROSPERO for English-language citations on ethnicity and COVID-19 (1 December 2019-15 May 2020). We also reviewed: COVID-19 articles in , clinical trial protocols, grey literature, surveillance data and preprint articles on COVID-19 in to evaluate if the association between ethnicity and clinical outcomes were reported and what they showed. PROSPERO:180654.

Findings

Of 207 articles in the database search, five reported ethnicity; two reported no association between ethnicity and mortality. Of 690 articles identified from medical journals, 12 reported ethnicity; three reported no association between ethnicity and mortality. Of 209 preprints, 34 reported ethnicity - 13 found Black, Asian and Minority Ethnic (BAME) individuals had an increased risk of infection with SARS-CoV-2 and 12 reported worse clinical outcomes, including ITU admission and mortality, in BAME patients compared to White patients. Of 12 grey literature reports, seven with original data reported poorer clinical outcomes in BAME groups compared to White groups.

Interpretation

Data on ethnicity in patients with COVID-19 in the published medical literature remains limited. However, emerging data from the grey literature and preprint articles suggest BAME individuals are at an increased risk of acquiring SARS-CoV-2 infection compared to White individuals and also worse clinical outcomes from COVID-19. Further work on the role of ethnicity in the current pandemic is of urgent public health importance.

Funding

NIHR.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WC Communicabable diseases
WF Respiratory system. Respiratory medicine
WG Cardiovascular system. Cardiology
WK Endocrine system. Endocrinology
Divisions: Clinical Support > Infectious Diseases
Related URLs:
Depositing User: Jamie Edgar
Date Deposited: 10 Jul 2020 12:43
Last Modified: 10 Jul 2020 12:43
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3257

Actions (login required)

View Item View Item