Outcomes of Cochlear Implantation in Patients with Pendred syndrome: A Systematic Review and Narrative Synthesis.

Biggs, Kirsty, Lovett, Amy, Metcalfe, Chris, Muzaffar, Jameel, Monksfield, Peter and Bance, Manohar (2020) Outcomes of Cochlear Implantation in Patients with Pendred syndrome: A Systematic Review and Narrative Synthesis. The journal of international advanced otology, 16 (3). pp. 432-442. ISSN 2148-3817. Full text available to UHB Athens account holders.

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Official URL: https://www.advancedotology.org/en/outcomes-of-coc...

Abstract

Establish outcomes following cochlear implantation (CI) in patients with Pendred syndrome. Systematic review and narrative synthesis. Databases searched: Medline, Pubmed, Embase, Web of Science, Cochrane Collection and ClinicalTrials.gov. No limits placed on language or year of publication. Review conducted in accordance with the PRISMA statement. Searches identified 251 abstracts and 242 full texts. Of these, 22 studies met inclusion criteria reporting outcomes in 231 patients with at least 234 implants. Hearing outcomes were generally good with patients experiencing useful functional improvement. A total of 46 minor complications were reported in 78 cases. The methodological quality of included studies was modest, predominantly consisting of case reports and non-controlled case series with small numbers of patients. All studies were OCEBM grade III-IV. Hearing outcomes following CI in Pendred syndrome are generally good with useful functional improvement. However, outcomes reported in published studies lack long term follow up.

Item Type: Article
Additional Information: Full text available to UHB Athens account holders.
Subjects: WV Otorhinolaryngology. ENT medicine
Divisions: Ambulatory Care > ENT
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Depositing User: Mr Philip O'Reilly
Date Deposited: 11 Nov 2020 11:34
Last Modified: 11 Nov 2020 11:34
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3642

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