New horizons for idiopathic intracranial hypertension: advances and challenges.

Mollan, Susan P, Grech, Olivia, Alimajstorovic, Zerin, Wakerley, Benjamin R and Sinclair, Alexandra J (2020) New horizons for idiopathic intracranial hypertension: advances and challenges. British medical bulletin. ISSN 1471-8391. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: http://bmb.oxfordjournals.org/

Abstract

INTRODUCTION

Idiopathic intracranial hypertension (IIH) is becoming a recognized condition due to the increasing incidence linked to a global obesity epidemic.

SOURCES OF DATA

All English papers on PubMed, Cochrane and Scholar between inception until 1 March 2020 were considered.

AREAS OF AGREEMENT

Studies suggest central adiposity has a pathogenic role. Recent weight gain is a risk factor and weight loss has a key role in management.

AREAS OF CONTROVERSY

Interpretation of abnormal lumbar puncture opening pressure is debated. There is an increasing recognition of obesity stigma and how this should be approached.

GROWING POINTS

Further evidence is required for the choice of surgical intervention for fulminant IIH. Education regarding IIH should be evidence based.

AREAS TIMELY FOR DEVELOPING RESEARCH

Novel research of the pathology of IIH is influencing development of therapies such as glucagon-like peptide-1 receptor agonists and targeting unique androgen signatures. The newly discovered cardiovascular risk requires further attention.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WK Endocrine system. Endocrinology
WL Nervous system. Neurology
WW Eyes. Ophthalmology
Divisions: Emergency Services > Neurology
Related URLs:
Depositing User: Jamie Edgar
Date Deposited: 23 Nov 2020 15:19
Last Modified: 17 Feb 2021 10:33
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3709

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