The Effect of Airway Management on CPR Quality in the Paramedic2 Randomised Controlled Trial.

Deakin, Charles D, Nolan, Jerry P, Ji, Chen, Fothergill, Rachael T, Quinn, Tom, Rosser, Andy, Lall, Ranjit and Perkins, Gavin D (2020) The Effect of Airway Management on CPR Quality in the Paramedic2 Randomised Controlled Trial. Resuscitation. ISSN 1873-1570.


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Good quality basic life support (BLS) is associated with improved outcome from cardiac arrest. Chest compression fraction (CCF) is a BLS quality indicator, which may be influenced by the type of airway used. We aimed to assess CCF according to the airway strategy in the PARAMEDIC2 study: no advanced airway, supraglottic airway (SGA), tracheal intubation, or a combination of the two. Our hypothesis was that tracheal intubation was associated with a decrease in the CCF compared with alternative airway management strategies.


PARAMEDIC2 was a multicentre double-blinded placebo-controlled trial of adrenaline vs placebo in out-of-hospital cardiac arrest. Data showing compression rate and ratio from patients recruited by London Ambulance Service (LAS) as part of this study was collated and analysed according to the advanced airway used during the resuscitation attempt.


CPR process data were available from 286/ 2058 (13.9%) of the total patients recruited by LAS. The mean compression rate for the first 5 min of data recording was the same in all groups (P = 0.272) and ranged from 104.2 (95%CI of mean: 100.5, 107.8) min to 108.0 (95%CI of mean: 105.1, 108.3) min. The mean compression fraction was also similar across all groups (P = 0.159) and ranged between 74.7% and 78.4%. There was no difference in the compression rates and fractions across the airway management groups, regardless of the duration of CPR.


There was no significant difference in the compression fraction associated with the airway management strategy.

Item Type: Article
Subjects: WB Practice of medicine > WB400 Intensive care
WG Cardiovascular system. Cardiology
Divisions: Emergency Services > Cardiology
Emergency Services > Emergency Department
Related URLs:
Depositing User: Mr Philip O'Reilly
Date Deposited: 26 Nov 2020 15:50
Last Modified: 26 Nov 2020 15:50

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