Complex Enterally Tube-Fed Community Patients Display Stable Tolerance, Improved Compliance and Better Achieve Energy and Protein Targets with a High-Energy, High-Protein Peptide-Based Enteral Tube Feed: Results from a Multi-Centre Pilot Study.

Green, Benjamin, Sorensen, Katy, Phillips, Mary, Green, Lisa, Watson, Rachel, McCallum, Adrienne, Brook, Sarah, Oldham, Siobhan, Barry, Michelle, Tomlinson, Lyndsey, Williams, Alice, Crease, Sam, Wills, Carrie, Talbot, Rose, Thomas, Rourke, Barker, Julie, Owen, Annalisa, Davies, Judith, Robinson, Carys, Lumsdon, Anna, Morris, Samm, McMurray, Chloé, Cunningham, Nicola, Miller, Lily, Day, Carolyn, Stanley, Kristina, Price, Susan, Duff, Susan, Julian, Anna, Thomas, Jennifer, Fleming, Carole-Anne, Hubbard, Gary and Stratton, Rebecca (2020) Complex Enterally Tube-Fed Community Patients Display Stable Tolerance, Improved Compliance and Better Achieve Energy and Protein Targets with a High-Energy, High-Protein Peptide-Based Enteral Tube Feed: Results from a Multi-Centre Pilot Study. Nutrients, 12 (11). ISSN 2072-6643. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Abstract

This pilot study evaluated a high-energy, high-protein, peptide-based, (medium-chain triglycerides) MCT-containing enteral tube feed (Nutrison Peptisorb Plus HEHP, Nutricia Ltd., Trowbridge, BA14 0XQ, UK.) containing 1.5 kcal/mL and 7.5 g protein/100 mL. Fifteen community-based, enterally tube-fed adults (42 (SD 16.3) years) received the intervention feed daily for 28 days, with gastrointestinal tolerance, compliance and nutrient intake assessed at baseline and after the intervention period. Incidence and intensity of constipation ( = 0.496), nausea ( = 1.000), abdominal pain ( = 0.366) and bloating ( = 0.250) remained statistically unchanged, yet the incidence and intensity of diarrhoea improved significantly after receiving the intervention feed (Z = -2.271, = 0.023). Compliance with the intervention feed was significantly greater compared to the patient's baseline regimens (99% vs. 87%, = 0.038). Compared to baseline, use of the intervention feed enabled patients to significantly increase total energy (1676 kcal/day (SD 449) to 1884 kcal/day (SD 537), = 0.039) and protein intake (73 g/day (SD 17) to 89 g/day (SD 23), = 0.001), allowing patients to better achieve energy (from 88% to 99%, = 0.038) and protein (from 101% to 121%, < 0.001) requirements. This pilot study demonstrates that a high-energy, high-protein, peptide-based, MCT-containing enteral tube feed maintains gastrointestinal tolerance and improves compliance, energy and protein intake in complex, enterally tube-fed, community-based adult patients, though more work is recommended to confirm this.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WA Patients. Primary care. Medical profession. Forensic medicine
WI Digestive system. Gastroenterology
Divisions: Planned IP Care > Gastroentrology
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Depositing User: Jamie Edgar
Date Deposited: 30 Nov 2020 11:53
Last Modified: 30 Nov 2020 11:53
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3739

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