The Impact of COVID-19 Pandemic on Adult and Pediatric Allergy & Immunology Services in the UK National Health Service.

Krishna, Mamidipudi Thirumala, Beck, Sarah C, Gribbin, Nathan, Nasser, Shuaib, Turner, Paul J, Hambleton, Sophie, Sargur, Ravishankar, Whyte, Andrew and Bethune, Claire (2020) The Impact of COVID-19 Pandemic on Adult and Pediatric Allergy & Immunology Services in the UK National Health Service. The journal of allergy and clinical immunology. In practice. ISSN 2213-2201. (In Press)

Full text not available from this repository.
Official URL:



The COVID-19 pandemic imposed multiple restrictions on healthcare services.


To investigate the impact of the pandemic on Allergy & Immunology (A&I) services in the UK.


National survey of all A&I services registered with the Royal College of Physicians and/or British Society for Allergy and Clinical Immunology. The survey covered staffing, facilities, personal protective equipment, appointments & patient review, investigations, treatments and research activity. Weeks commencing 03 Feb'20 (pre-COVID), 06 April'20 and 08'May'20 were used as reference points for the dataset.


99 services participated. There was a reduction in nursing, medical, administrative and allied health professional staff during pandemic; 86% and 92% of A&I services continued to accept non-urgent and urgent referrals respectively during the pandemic. There were changes in immunoglobulin (Ig) dose and infusion regimen in 67% and 14% of adult and pediatric services respectively; 30% discontinued immunoglobulin replacement in some patients. There was a significant (all variables, p≤0.0001) reduction in the following: face-to-face consultations (increase in telephone consultations), initiation of venom immunotherapy, sublingual and subcutaneous injection immunotherapy, anesthetic allergy testing and hospital procedures (food challenges, immunoglobulin and omalizumab, administration); and a significant increase (p≤0.0001) in home therapy for immunoglobulin and omalizumab. Adverse clinical outcomes were reported, but none were serious.


The pandemic had significant impact on A&I services leading to multiple unplanned pragmatic amendments in service delivery. There is an urgent need for prospective audits and strategic planning in the medium and long term to achieve equitable, safe and standardised healthcare.

Item Type: Article
Subjects: QW Microbiology. Immunology
WC Communicabable diseases
WD Diseases and disorders of systemic, metabolic or environmental origin > WD300 Hypersensitivity. Allergy
Divisions: Clinical Support > Immunology
Related URLs:
Depositing User: Mrs Yolande Brookes
Date Deposited: 04 Dec 2020 14:58
Last Modified: 04 Dec 2020 15:50

Actions (login required)

View Item View Item