Grand round: Autoimmune hepatitis.

Trivedi, Palak J, Hubscher, Stefan G, Heneghan, Michael, Gleeson, Dermot and Hirschfield, Gideon M (2019) Grand round: Autoimmune hepatitis. Journal of hepatology, 70 (4). pp. 773-784. ISSN 1600-0641. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs.

Full text not available from this repository.
Official URL: https://www.journal-of-hepatology.eu/article/S0168...

Abstract

Autoimmune hepatitis is a corticosteroid-responsive liver disease arising consequent to immunogenetic and environmental risk factors. The clinical course reflects relapsing and remitting, hepatocyte targeted immunologic damage, which is countered by reparative responses to cell injury. Appropriate and timely immunosuppressive therapy drives the disease into remission, albeit with inevitable side effects. Many challenges faced in the clinic reflect practice that must capture a heterogeneous disease presentation, course, and treatment response, as well as treatment tolerability. In this Grand Round we appraise the evidence supporting current treatment approaches, address the impact of autoimmune liver disease 'crossover or overlap' presentations, explore important clinical correlates to immune-serological classifiers, and discuss the factors influencing choice of alternative therapy in difficult-to-treat situations.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs.
Subjects: QY Clinical pathology
WC Communicabable diseases
Divisions: Clinical Support
Clinical Support > Pathology
Related URLs:
Depositing User: Mrs Noomi Tyholdt-Pidgley
Date Deposited: 08 Jan 2021 15:15
Last Modified: 08 Jan 2021 15:15
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3811

Actions (login required)

View Item View Item