Administrative coding in electronic health care record-based research of NAFLD: an expert panel consensus statement.

Hagström, Hannes, Adams, Leon A, Allen, Alina M, Byrne, Christopher D, Chang, Yoosoo, Grønbaek, Henning, Ismail, Mona, Jepsen, Peter, Kanwal, Fasiha, Kramer, Jennifer, Lazarus, Jeffrey V, Long, Michelle T, Loomba, Rohit, Newsome, Philip N, Rowe, Ian A, Ryu, Seungho, Schattenberg, Jörn M, Serper, Marina, Sheron, Nick, Simon, Tracey G, Tapper, Elliot B, Wild, Sarah, Wong, Vincent Wai-Sun, Yilmaz, Yusuf, Zelber-Sagi, Shira and Åberg, Fredrik (2021) Administrative coding in electronic health care record-based research of NAFLD: an expert panel consensus statement. Hepatology (Baltimore, Md.). ISSN 1527-3350. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: http://onlinelibrary.wiley.com/journal/10.1002/(IS...

Abstract

BACKGROUND AND AIMS

Electronic health record (EHR)-based research allows the capture of large amounts of data, which is necessary in nonalcoholic fatty liver disease (NAFLD), where the risk of clinical liver outcomes is generally low. The lack of consensus on which International Classification of Disease (ICD) codes should be used as exposures and outcomes limits comparability and generalizability of results across studies. We aimed to establish consensus among a panel of experts on ICD codes that could become the reference standard and provide guidance around common methodological issues.

APPROACH AND RESULTS

Researchers with an interest in EHR-based NAFLD research were invited to collectively define which administrative codes are most appropriate for documenting exposures and outcomes. We used a modified Delphi approach to reach consensus on several commonly encountered methodological challenges in the field. After two rounds of revision, a high level of agreement (>67%) was reached on all items considered. Full consensus was achieved on a comprehensive list of administrative codes to be considered for inclusion and exclusion criteria in defining exposures and outcomes in EHR-based NAFLD research. We also provide suggestions on how to approach commonly encountered methodological issues and identify areas for future research.

CONCLUSIONS

This expert panel consensus statement can help harmonize and improve generalizability of EHR-based NAFLD research.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WD Diseases and disorders of systemic, metabolic or environmental origin
WD Diseases and disorders of systemic, metabolic or environmental origin > WD10 Diet and nutrition
WD Diseases and disorders of systemic, metabolic or environmental origin > WD250 Metabolic diseases
WI Digestive system. Gastroenterology
Divisions: Planned IP Care > Gastroentrology
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Depositing User: Jamie Edgar
Date Deposited: 03 Feb 2021 11:40
Last Modified: 03 Feb 2021 11:40
URI: http://www.repository.uhblibrary.co.uk/id/eprint/3930

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