Sarcopenia in Inflammatory Bowel Disease: A Narrative Overview.

Dhaliwal, Amritpal, Quinlan, Jonathan I, Overthrow, Kellie, Greig, Carolyn A, Lord, Janet M, Armstrong, Matthew J and Cooper, Sheldon C (2021) Sarcopenia in Inflammatory Bowel Disease: A Narrative Overview. Nutrients, 13 (2). ISSN 2072-6643. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Abstract

Malnutrition is a common condition encountered in patients with inflammatory bowel disease (IBD) and is often associated with sarcopenia (the reduction of muscle mass and strength) which is an ever-growing consideration in chronic diseases. Recent data suggest the prevalence of sarcopenia is 52% and 37% in Crohn's disease and ulcerative colitis, respectively, however it is challenging to fully appreciate the prevalence of sarcopenia in IBD. Sarcopenia is an important consideration in the management of IBD, including the impact on quality of life, prognostication, and treatment such as surgical interventions, biologics and immunomodulators. There is evolving research in many chronic inflammatory states, such as chronic liver disease and rheumatoid arthritis, whereby interventions have begun to be developed to counteract sarcopenia. The purpose of this review is to evaluate the current literature regarding the impact of sarcopenia in the management of IBD, from mechanistic drivers through to assessment and management.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WE Musculoskeletal. Orthopaedics
WI Digestive system. Gastroenterology
WT Geriatrics. Elderly care
Divisions: Planned IP Care > Gastroentrology
Related URLs:
Depositing User: Jamie Edgar
Date Deposited: 15 Mar 2021 10:45
Last Modified: 15 Mar 2021 10:45
URI: http://www.repository.uhblibrary.co.uk/id/eprint/4086

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