The Role of Uric Acid in the Acute Myocardial Infarction: A Narrative Review.

Demiray, Atalay, Afsar, Baris, Covic, Adrian, Kuwabara, Masanari, Ferro, Charles J, Lanaspa, Miguel A, Johnson, Richard J and Kanbay, Mehmet (2021) The Role of Uric Acid in the Acute Myocardial Infarction: A Narrative Review. Angiology. p. 33197211012546. ISSN 1940-1574. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Abstract

Increased serum uric acid (SUA) levels have been associated with various pathologic processes such as increased oxidative stress, inflammation, and endothelial dysfunction. Thus, it is not surprising that increased SUA is associated with various adverse outcomes including cardiovascular (CV) diseases. Recent epidemiological evidence suggests that increased SUA may be related to acute myocardial infarction (AMI). Accumulating data also showed that elevated UA has pathophysiological role in the development of AMI. However, there are also studies showing that SUA is not related to the risk of AMI. In this narrative review, we summarized the recent literature data regarding SUA and AMI after providing some background information for the association between UA and coronary artery disease. Future studies will show whether decreasing SUA levels is beneficial for outcomes related to AMI and the optimum SUA levels for best outcomes in CV diseases.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WG Cardiovascular system. Cardiology
WJ Urogenital system. Urology
Divisions: Emergency Services > Renal
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Depositing User: Jamie Edgar
Date Deposited: 05 May 2021 15:14
Last Modified: 05 May 2021 15:14
URI: http://www.repository.uhblibrary.co.uk/id/eprint/4278

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