Cost-effectiveness of bariatric surgery versus community weight management to treat obesity-related idiopathic intracranial hypertension: evidence from a single-payer healthcare system.

Elliot, Laura, Frew, Emma, Mollan, Susan P, Mitchell, James L, Yiangou, Andreas, Alimajstorovic, Zerin, Ottridge, Ryan S, Wakerley, Ben R, Thaller, Mark, Grech, Olivia, Singhal, Rishi, Tahrani, Abd A, Harrison, Mark, Sinclair, Alexandra J and Aguiar, Magda (2021) Cost-effectiveness of bariatric surgery versus community weight management to treat obesity-related idiopathic intracranial hypertension: evidence from a single-payer healthcare system. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. ISSN 1878-7533.

Full text not available from this repository.
Official URL: http://www.elsevier.com/wps/product/cws_home/70377...

Abstract

BACKGROUND

Idiopathic intracranial hypertension (IIH) is associated with significant morbidity, predominantly affecting women of childbearing age living with obesity. Weight loss has demonstrated successful disease-modifying effects; however, the long-term cost-effectiveness of weight loss interventions for the treatment of IIH has not yet been established.

OBJECTIVES

To estimate the cost-effectiveness of weight-loss treatments for IIH.

SETTING

Single-payer healthcare system (National Health Service, England).

METHODS

A Markov model was developed comparing bariatric surgery with a community weight management intervention over 5-, 10-, and 20-year time horizons. Transition probabilities, utilities, and resource use were informed by the IIH Weight Trial (IIH:WT), alongside the published literature. A probabilistic sensitivity analysis was conducted to characterize uncertainty within the model.

RESULTS

In the base case analysis, over a 20-year time horizon, bariatric surgery was "dominant," led to cost savings of £49,500, and generated an additional 1.16 quality-adjusted life years in comparison to the community weight management intervention. The probabilistic sensitivity analysis indicated a probability of 98% that bariatric surgery is the dominant option in terms of cost-effectiveness.

CONCLUSION

This economic modeling study has shown that when compared to community weight management, bariatric surgery is a highly cost-effective treatment option for IIH in women living with obesity. The model shows that surgery leads to long-term cost savings and health benefits, but that these do not occur until after 5 years post surgery, and then gradually increase over time.

Item Type: Article
Subjects: WO Surgery
Divisions: Planned IP Care > General Surgery
Related URLs:
Depositing User: Miss Emily Johnson
Date Deposited: 10 May 2021 13:22
Last Modified: 10 May 2021 13:22
URI: http://www.repository.uhblibrary.co.uk/id/eprint/4295

Actions (login required)

View Item View Item