Correlation Between Thyroid Fine Needle Aspiration Cytology and Postoperative Histology: A 10-Year Single-Centre Experience.

Abou-Foul, Ahmad K, Muzaffar, Jameel, Diakos, Emmanuel, Best, James E, Momtahan, Navid and Jayaram, Sharan (2021) Correlation Between Thyroid Fine Needle Aspiration Cytology and Postoperative Histology: A 10-Year Single-Centre Experience. Cureus, 13 (4). e14504. ISSN 2168-8184.

Full text not available from this repository.
Official URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC81239...

Abstract

Introduction Fine needle aspiration cytology (FNAC) forms part of the routine workup for suspicious thyroid nodules. Whilst cytological analysis is less precise than histological assessment, it is quick and easy to perform and may avoid the need for invasive and potentially risky surgery. Methods This retrospective study spanned a 10-year period comparing preoperative FNAC with postoperative histology results to establish the accuracy of diagnosis and malignancy rates within our population. These results were then compared to the published figures in the literature. Results The histological reports of 659 consecutive cases of thyroid surgery between 2006 and 2015 were retrieved from our hospital database. Among the 471 patients (71.5%) who underwent preoperative FNAC, the postoperative histology was reported as benign in 352 (74.7%) and malignant in 119 cases (25.3%). Papillary thyroid cancer (PTC) was the commonest histological diagnosis. Thy1 grade was reported in 165 (30%) cases, with 19.4% having a final histological diagnosis of malignancy. In the Thy2 group, 85.3% of patients had a benign final histological diagnosis, while 14.7% had malignancy (false-negative results). Malignancy was found in 89% of Thy4 and 100% of Thy5 group patients.  Conclusions Rates of malignancy varied considerably from those in the published literature. Each centre should be able to quote a local malignancy rate during patient counselling. It is also prudent for all units performing thyroid diagnostics to investigate the factors that might lead to inaccuracies in reporting.

Item Type: Article
Subjects: QY Clinical pathology
WV Otorhinolaryngology. ENT medicine
Divisions: Ambulatory Care > ENT
Related URLs:
Depositing User: Miss Emily Johnson
Date Deposited: 04 Jun 2021 09:18
Last Modified: 04 Jun 2021 09:18
URI: http://www.repository.uhblibrary.co.uk/id/eprint/4367

Actions (login required)

View Item View Item