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Islam, Shofiq, Al Maqbali, T, Howe, D J and Campbell, J (2014) Hypocalcaemia following total thyroidectomy: early post-operative parathyroid hormone assay as a risk stratification and management tool. The Journal of laryngology and otology, 128 (3). pp. 274-8. ISSN 1748-5460.
Full text not available from this repository.Abstract
OBJECTIVE
To develop a practical, efficient and predictive algorithm to manage potential or actual post-operative hypocalcaemia after complete thyroidectomy, using a single post-operative parathyroid hormone assay.
METHODS
This paper reports a prospective study of 59 patients who underwent total or completion thyroidectomy over a period of 24 months. Parathyroid hormone levels were checked post-operatively on the day of surgery, and all patients were evaluated for hypocalcaemia both clinically and biochemically with serial corrected calcium measurements.
RESULTS
No patient with an early post-operative parathyroid hormone level of 23 ng/l or more (i.e. approximately twice the lower limit of the normal range) developed hypocalcaemia. All the patients who initially had post-operative hypocalcaemia but had an early parathyroid hormone level of 8 ng/l or more (i.e. approximately two-thirds of the lower limit of the normal range) had complete resolution of their hypocalcaemia within three months.
CONCLUSION
Early post-operative parathyroid hormone measurement can reliably predict patients at risk of post-thyroidectomy hypocalcaemia, and predict those patients expected to recover from temporary hypocalcaemia. A suggested post-operative management algorithm is presented.
| Item Type: | Article |
|---|---|
| Subjects: | WK Endocrine system. Endocrinology |
| Divisions: | Ambulatory Care > ENT |
| Related URLs: | |
| Depositing User: | Mrs Yolande Brookes |
| Date Deposited: | 19 Aug 2014 10:05 |
| Last Modified: | 19 Aug 2014 10:05 |
| URI: | http://www.repository.uhblibrary.co.uk/id/eprint/533 |
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