Smartphone detection of atrial fibrillation using photoplethysmography: a systematic review and meta-analysis.

Gill, Simrat K, Bunting, Karina V, Sartini, Claudio, Cardoso, Victor Roth, Ghoreishi, Narges, Uh, Hae-Won, Williams, John A, Suzart-Woischnik, Kiliana, Banerjee, Amitava, Asselbergs, Folkert W, Eijkemans, Mjc, Gkoutos, Georgios V and Kotecha, Dipak (2022) Smartphone detection of atrial fibrillation using photoplethysmography: a systematic review and meta-analysis. Heart (British Cardiac Society). ISSN 1468-201X. This article is available to all UHB staff and students login using a UHB Athens Account. Register for Athens here - https://openathens.nice.org.uk/

Full text not available from this repository.
Official URL: http://heart.bmj.com/

Abstract

OBJECTIVES

Timely diagnosis of atrial fibrillation (AF) is essential to reduce complications from this increasingly common condition. We sought to assess the diagnostic accuracy of smartphone camera photoplethysmography (PPG) compared with conventional electrocardiogram (ECG) for AF detection.

METHODS

This is a systematic review of MEDLINE, EMBASE and Cochrane (1980-December 2020), including any study or abstract, where smartphone PPG was compared with a reference ECG (1, 3 or 12-lead). Random effects meta-analysis was performed to pool sensitivity/specificity and identify publication bias, with study quality assessed using the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies-2) risk of bias tool.

RESULTS

28 studies were included (10 full-text publications and 18 abstracts), providing 31 comparisons of smartphone PPG versus ECG for AF detection. 11 404 participants were included (2950 in AF), with most studies being small and based in secondary care. Sensitivity and specificity for AF detection were high, ranging from 81% to 100%, and from 85% to 100%, respectively. 20 comparisons from 17 studies were meta-analysed, including 6891 participants (2299 with AF); the pooled sensitivity was 94% (95% CI 92% to 95%) and specificity 97% (96%-98%), with substantial heterogeneity (p<0.01). Studies were of poor quality overall and none met all the QUADAS-2 criteria, with particular issues regarding selection bias and the potential for publication bias.

CONCLUSION

PPG provides a non-invasive, patient-led screening tool for AF. However, current evidence is limited to small, biased, low-quality studies with unrealistically high sensitivity and specificity. Further studies are needed, preferably independent from manufacturers, in order to advise clinicians on the true value of PPG technology for AF detection.

Item Type: Article
Additional Information: This article is available to all UHB staff and students login using a UHB Athens Account. Register for Athens here - https://openathens.nice.org.uk/
Subjects: QA Mathematics. Computing
QU Biochemistry
QV Pharmacology
QZ Pathology. Oncology
W Public health. Health statistics. Occupational health. Health education
WA Patients. Primary care. Medical profession. Forensic medicine
WG Cardiovascular system. Cardiology
Divisions (November 2021 Onwards): Cardiology
Research and Development
Related URLs:
Depositing User: Lotty Summers
Date Deposited: 25 Mar 2022 14:53
Last Modified: 25 Mar 2022 14:53
URI: http://www.repository.uhblibrary.co.uk/id/eprint/5332

Actions (login required)

View Item View Item