Gill, Simrat K, Bunting, Karina V, Sartini, Claudio, Cardoso, Victor Roth, Ghoreishi, Narges, Uh, Hae-Won, Williams, John A, Suzart-Woischnik, Kiliana, Banerjee, Amitava, Asselbergs, Folkert W, Eijkemans, Mjc, Gkoutos, Georgios V and Kotecha, Dipak (2022) Smartphone detection of atrial fibrillation using photoplethysmography: a systematic review and meta-analysis. Heart (British Cardiac Society). ISSN 1468-201X. This article is available to all UHB staff and students login using a UHB Athens Account. Register for Athens here - https://openathens.nice.org.uk/
Full text not available from this repository.Abstract
OBJECTIVES
Timely diagnosis of atrial fibrillation (AF) is essential to reduce complications from this increasingly common condition. We sought to assess the diagnostic accuracy of smartphone camera photoplethysmography (PPG) compared with conventional electrocardiogram (ECG) for AF detection.
METHODS
This is a systematic review of MEDLINE, EMBASE and Cochrane (1980-December 2020), including any study or abstract, where smartphone PPG was compared with a reference ECG (1, 3 or 12-lead). Random effects meta-analysis was performed to pool sensitivity/specificity and identify publication bias, with study quality assessed using the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies-2) risk of bias tool.
RESULTS
28 studies were included (10 full-text publications and 18 abstracts), providing 31 comparisons of smartphone PPG versus ECG for AF detection. 11 404 participants were included (2950 in AF), with most studies being small and based in secondary care. Sensitivity and specificity for AF detection were high, ranging from 81% to 100%, and from 85% to 100%, respectively. 20 comparisons from 17 studies were meta-analysed, including 6891 participants (2299 with AF); the pooled sensitivity was 94% (95% CI 92% to 95%) and specificity 97% (96%-98%), with substantial heterogeneity (p<0.01). Studies were of poor quality overall and none met all the QUADAS-2 criteria, with particular issues regarding selection bias and the potential for publication bias.
CONCLUSION
PPG provides a non-invasive, patient-led screening tool for AF. However, current evidence is limited to small, biased, low-quality studies with unrealistically high sensitivity and specificity. Further studies are needed, preferably independent from manufacturers, in order to advise clinicians on the true value of PPG technology for AF detection.
Item Type: | Article |
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Additional Information: | This article is available to all UHB staff and students login using a UHB Athens Account. Register for Athens here - https://openathens.nice.org.uk/ |
Subjects: | QA Mathematics. Computing QU Biochemistry QV Pharmacology QZ Pathology. Oncology W Public health. Health statistics. Occupational health. Health education WA Patients. Primary care. Medical profession. Forensic medicine WG Cardiovascular system. Cardiology |
Divisions (November 2021 Onwards): | Cardiology Research and Development |
Related URLs: | |
Depositing User: | Lotty Summers |
Date Deposited: | 25 Mar 2022 14:53 |
Last Modified: | 25 Mar 2022 14:53 |
URI: | http://www.repository.uhblibrary.co.uk/id/eprint/5332 |
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