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Crooks, Neil H, Patel, Jaimin, Diwakar, Lavanya and Smith, Fang Gao (2014) Icatibant in the treatment of Angiotensin-converting enzyme inhibitor-induced angioedema. Case reports in critical care, 2014. p. 864815. ISSN 2090-6420.
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Icatibant in the treatment of Angiotensin-converting enzyme inhibitor-induced angioedema.pdf Download (2MB) | Preview |
Abstract
We describe the case of a 75-year-old woman who presented with massive tongue and lip swelling secondary to angiotensin-converting enzyme inhibitor-induced angioedema. An awake fibre-optic intubation was performed because of impending airway obstruction. As there was no improvement in symptoms after 72 hours, the selective bradykinin B2 receptor antagonist icatibant (Firazyr) was administered and the patient's trachea was successfully extubated 36 hours later. To our knowledge this is the first documented case of icatibant being used for the treatment of angiotensin-converting enzyme inhibitor-induced angioedema in the United Kingdom and represents a novel therapeutic option in its management.
| Item Type: | Article |
|---|---|
| Subjects: | WG Cardiovascular system. Cardiology |
| Divisions: | Emergency Services > Cardiology |
| Related URLs: | |
| Depositing User: | Mr Philip O'Reilly |
| Date Deposited: | 20 May 2015 14:50 |
| Last Modified: | 20 May 2015 14:50 |
| URI: | http://www.repository.uhblibrary.co.uk/id/eprint/924 |
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